Pires was born in Lisbon, Portugal. Her first recital was at the age of five, and at the age of seven she was already playing Mozart piano concertos publicly. Two years later she received Portugal’s top prize for young musicians. In the following years, she studied with Campos Coelho at the Lisbon Conservatory, taking courses in composition, theory, and history of music. She continued her studies in Germany, first in the Musikakademie of Munich with Rosl Schmidt and then in Hanover with Karl Engel.